PAEDIATRIC ADRENOCORTICAL CARCINOMA: A CASE REPORT

Adrenocortical carcinoma (ACC) is a relatively rare but an aggressive neoplasm that can have variety of manifes­tations. It manifest in the form virilization, hyperaldosteronism, cushingoid features or combination that. Due to rapid appearance signs and symptoms children, these tumours be diagnosed early however if delayed bear worse prognosis as they tend metastasize course disease progression. We report case 4 years old female patient from Chitral, Pakistan who was referred Endocrinology Department Paediatric Hayatabad Medical Complex, Peshawar Patient presented at paediatric OPD with com­plaints weight gain, hirsutism, rashes over face acne. had typical moon facies, buffalo hump distended abdomen without striae well mass left hypochondrium on examination. On further evaluation clitoromegaly pubic hair tanner stage were found. Both Ultrasound CT-Scan showed supra-renal soft tissue invading inferior venacava (IVC). She evaluated her overnight dexamethasone suppression test (ODST) serum testosterone levels high although sodium potassium normal ruling out hyperaldosteronism. Next, biopsy performed which consistent adrenocortical carcinoma. ACC highly tumor requires detection diagnosis specially children. If may not favourable. therefore avid clinical suspicion proceed onto diagnostic lines for patient’s benefit physician’s satisfaction.